Road network is one of the most rapidly-developing branches of the regional economy. The length of the public federal, regional and inter-municipal and local highways exceeds 35 thousand km., including:
- 716 km of federal highways;
- 7533 km of regional and inter-municipal highways owned by the region,
- 27110 km of local roads owned by the municipalities.
City road network in municipalities comprises 246159,3 sq. km.
Within the preparation to FIFA World Cup 2018 games the left bank of the river Don area is actively developing.